Signals

AstraZeneca’s heart drug failure raises a brutal question: how much treatment is too much treatment?
AstraZeneca and Ionis’ eplontersen did not reduce cardiovascular death and recurrent cardiovascular events in the overall CARDIO-TTRansform population. With 57% of participants already receiving a transthyretin stabiliser and another 24% starting one during the study, the result raises a harder question than whether one drug failed: how should regulators and payers judge added benefit when…

Not All Eye Infections Are Equal: New Evidence Points to a Precision Medicine Approach

What happens when surgeons no longer need to be in the same country as their patients?

EMA backs first oral obesity GLP-1 as pills push treatment towards mass-market adoption

As GLP-1 use expands, healthcare systems are confronting a new challenge: balancing obesity treatment with rising concerns about eating disorders and patient safety.

J&J’s Firefly Bio Deal Puts KRAS Back Into the Oncology Arms Race

Parkinson’s Research Takes Aim at Mitochondrial Failure

Ebola Control Hits the Trust Test

The invisible heart disease crisis: Why congenital heart disease is moving up the global health agenda

A new guideline is changing how health systems think about obesity, diabetes and heart disease
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