Signals

Fasted cardio burns more fat during exercise, but the long-term advantage disappears
Exercising before breakfast increases fat oxidation during a workout, a physiological effect that has helped turn fasted cardio into a recurring weight-loss trend. Longer-term research, however, has not shown that this acute metabolic shift produces greater body-fat loss than exercising after eating, highlighting a wider problem in fitness and metabolic health

Oral GLP-1 drugs could widen access, but high prices may do the opposite

Boehringer Ingelheim is adding a third target to obesity treatment.

Alzheimer’s Pill Has Finished the Trial. Evidence Has Not.

The weight came back. Some visceral fat did not. Obesity care may be measuring the wrong outcome

China Just Put a Bispecific ADC Into Esophageal Cancer

Prevention Is Now Alzheimer’s Hardest Trial

The ovaries were never the whole story: PMOS linked to heart attacks and strokes in more than two million women

The Novo Nordisk Foundation is going global on cardiometabolic disease.

Liver Cancer Is Moving Beyond TACE Alone
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