Signals

Microglia Are Not a Shortcut to Alzheimer’s Certainty
Sanofi’s oral TREM2 agonist SAR448851 is moving toward Phase II testing in early Alzheimer’s disease. The mechanism is compelling. The field has already learned that TREM2 biology can disappoint.

The Money Is Moving Into Cancer Screening. The Evidence Still Has to Catch Up.

Huntington’s Needs More Than a Better Curve

New nicotine products could become the next major cardiovascular policy failure

Childhood obesity is the next cardiometabolic crisis already unfolding

Neurology Is Trying to Stop Nerves Dying, Not Just Treat What Is Left

South Sudan Has a New Health Deal. Now It Needs a Delivery System.

AI Improved Sepsis Compliance. Patients Still Need the Outcome Proof.

Cardiac rehab saves lives. Health systems still treat it like optional aftercare

BMI is not enough. Cardiometabolic risk is hiding in where fat lives
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